منابع مشابه
Mechanochemistry of Cardiac Muscle
The aim of this study was to evaluate utilization of chemical energy in relation to myocardial mechanics in variably afterloaded contractions of cardiac muscle by determining total energy utilization (—P) in the absence of energy production. Right ventricular papillary muscles of cats were equilibrated at 26°C in a myograph in Krebs' solution while contracting isometrically (12/ min). Following...
متن کاملThe Mechanochemistry of Cardiac Muscle
The utilization of creatine phosphate (CP) and adenosine triphosphate (ATP) was studied in the iodoacetate (IAA) and nitrogen (N(2))-treated cat papillary muscle. Under these conditions the net production of ATP does not occur, and the net utilization of ATP is reflected in a fall in CP concentration. The rate of energy utilization of the IAA-N(2)-treated cat papillary muscle resting without te...
متن کاملMechanochemistry of cardiac muscle. V. Influence of thyroid state on energy utilization.
The possibility that alterations in the rate or efficiency of energy utilization could be involved in the control of cellular oxygen consumption by thyroid hormone was examined in right ventricular papillary muscles isolated from normal euthyroid cats and cats with experimentally induced hyperthyroidism and hypothyroidism. Energy production in the muscles was inhibited and isolated from the pro...
متن کاملMechanochemistry of cardiac muscle. IV. Utilization of high-energy phosphates in experimental heart failure in cats.
This investigation was designed to determine whether a defect in energy utilization exists in heart failure. Accordingly, the direct conversion of chemical energy to mechanical work was studied in right ventricular papillary muscles from normal cats and cats with experimental right ventricular failure secondary to pulmonary artery constriction. Energy production was inhibited by iodoacetic acid...
متن کاملMechanochemistry
The scientific community’s general interest in using mechanical energy to trigger or facilitate chemical reactivity has been growing at a speedy pace. In particular, in recent years, organic chemistry has witnessed a constant flow of examples where the use of mechanochemical techniques proved not only to outperform traditional solution-based methodologies, but also enabled access to otherwise i...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1968
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.22.4.465